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NemaLife News

  • Writer's pictureLevi Glover

April 2024 Industry News


Unveiling the Future of Botanical Supplements with Cutting-edge Technology

 

Dive into the world of botanical product integrity with us! Our latest blog explores the challenge of providing assurance that the botanical material formulated into the finished product provides the expected physiological effect. Discover how NemaLife's organism-on-chip platform is bridging this gap for the botanical industry.  #BotanicalIntegrity #CElegans #physiologicaldata  Read More. 

 

A probiotic from Chinese pickles improves lifespan in C. elegans

 

This study explores the antiaging effects of Lactobacillus fermentum strain WC2020 in Caenorhabditis elegans (C. elegans). WC2020 extends the lifespan of C. elegans by enhancing mitochondrial function, reducing oxidative stress, and activating the JNK/DAF-16 pathway. These effects are specific to WC2020 and not observed in mutants lacking the JNK gene. The findings suggest that WC2020 could be a promising probiotic for promoting longevity and health through the JNK-mediated antioxidant pathway, offering potential applications in food supplements and bioprocessing.  Read More.

 

How to freeze a memory: putting worms on ice stops them forgetting

 

A recent study on roundworms, Caenorhabditis elegans, reveals intriguing insights into memory retention. When placed on ice, these worms retain memories for up to 16 hours, but lose them rapidly once returned to room temperature. Surprisingly, pre-cooling or administering lithium helps prolong memory retention even at room temperature. Researchers identified a signaling molecule, diacylglycerol, as a potential "forgetting switch" regulating memory loss. Furthermore, they observed that membrane rigidity affects memory retention, with stiffer membranes delaying forgetfulness.   Read More.

 

Gut-associated functions are favored during microbiome assembly across a major part of C. elegans life

 

This study delves into the complex relationship between host biology and the microbiome, focusing on the nematode Caenorhabditis elegans. Through controlled experiments, researchers observed shifts in bacterial community composition over the worm's lifetime, with younger animals displaying more selective effects compared to older ones. The adult microbiome is found to be enriched in specific bacterial genera, suggesting benefits for the worm. By employing various analytical methods, the study highlights the importance of both stochastic processes and metabolic characteristics in microbiome assembly dynamics. Interestingly, the findings indicate that the host may actively influence its microbiome composition. Read More.

 

Effects of dietary fibre on metabolic health and obesity

 

This article delves into the complex dynamics of obesity and metabolic syndrome, highlighting the role of hormonal, neural, and metabolic pathways, as well as environmental factors, in regulating body weight. It emphasizes the significant impact of the gut microbiota on energy balance and discusses the proven benefits of dietary fiber in managing obesity. Additionally, the article explores the interaction between fiber and the gut microbiota in weight regulation and touches on the potential of precision medicine approaches to predict individual responses to fiber supplementation based on microbiota and clinical characteristics. Read More.

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